Impaired emotion recognition in Cntnap2-deficient mice is …
WEB3 days ago · In contrast, both WT and KO mice showed normal behavior in the SP task, ... but at 30 Hz. Before the experiments, the mice were lightly anesthetized with isoflurane and connected to the laser (473 ...
Novelty Seeking and Stereotypic Activation of Behavior in Mice …
WEBApr 27, 2005 · Although open field (OF) activity is similar for WT and HZ animals, it is enhanced for KO mice. The purpose of the present investigations was to study spontaneously emitted behaviors and to...
40 Hz light flickering facilitates the glymphatic flow via adenosine ...
WEBAug 6, 2024 · We first evaluated the frequency-dependent effects of light flickering on glymphatic influx in wild-type (WT) mice, by injecting a CSF fluorescent tracer (Y39-1, 2 kDa) into the subarachnoid...
Intellectual Disability and Brain Creatine Deficit: Phenotyping of …
WEBAug 2, 2021 · The GAMT knockout (KO) mouse model presents biochemical alterations in bodily fluids, the brain, and muscles, including increased GAA and decreased Cr and creatinine (Crn) levels, which are similar to those observed in humans.
Aberrant slow waves in the hippocampus during activation in mice …
WEBSep 14, 2021 · The effects of acetylcholine on cortical activation were studied in wild-type (WT) mice, compared to knockout (KO) mice depleted of the vesicular acetylcholine transporter (VAChT) gene in the basal forebrain, and knockdown (KD) mice with heterogeneous depletion of VAChT gene in the brain.
Neural precursor cells rescue symptoms of Rett syndrome by …
WEB5 hours ago · Asterisk denotes a significant difference between KO+NPCs and KO + PBS mice. The difference between KO + PBS and WT + PBS mice, or KO+NPCs and WT + PBS is omitted, although significant at all time-points, excluding at day −5. *p = 0.0257, ***p = 0.0002 by two-way ANOVA followed by Tukey post-hoc test.
Lack of Evidence for Vesicular Glutamate Transporter Expression in ...
WEBMar 6, 2013 · As a first step, we therefore systematically re-investigated VGLUT1–3 immunostaining in cultured astrocytes from WT, HZ, and KO littermates, and studied the expression of fluorescent protein by cultured astrocytes from VGLUT1 Venus KI and VGLUT2-EGFP mice.
Behavioral phenotyping of glutathione-deficient mice: …
WEBJan 15, 2012 · Compared to WT and HZ, GCLM-KO mice displayed enhanced locomotor activity in the open field. In contrast, the level and pattern of activity in the home cage was normal. This suggests that the observed hyperlocomotion was selectively expressed in response to environmental novelty.
Altered EEG power spectrum, but not sleep-wake architecture, in …
WEBFeb 2, 2023 · We conducted polysomnographic recordings of Hcn1 constitutive knockout ( Hcn1 KO) and wild-type (WT) mice in order to investigate the potential role of HCN1 channels in sleep/wake regulation. EEG and EMG data were analysed using the Somnivore ™ machine learning algorithm.
Novelty seeking and stereotypic activation of behavior in mice …
WEBAlthough open field (OF) activity is similar for WT and HZ animals, it is enhanced for KO mice. The purpose of the present investigations was to study spontaneously emitted behaviors and to determine the behavioral and neurochemical mechanisms that may contribute to the hyperactivity of KO animals.
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