Dozens of labs around the world are striving to grow models of human embryos to study development, fertility and therapies.

Studying human embryonic development is complicated for several reasons. Models derived from pluripotent stem cells ...

Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...

When they become fathers, men who have an unhealthy, high-cholesterol diet can cause increased risk of cardiovascular disease ...

Scientists at the IMB have identified 5-formylcytosine (5fC) as an activating epigenetic mark that initiates gene expression ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication.

Chondrocyte columns, which are a hallmark of growth plate architecture, play a central role in bone elongation. Columns are formed by clonal expansion following rotation of the division plane, ...

A woman's ovaries are like a factory where eggs grow and produce hormones that regulate everything from menstruation and ...

As immature egg cells, called oocytes get older, they begin having problems with cell division. This can result in aneuploidy ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

This raises the distant possibility of doing the same for people--although experts caution that very few mouse embryos were born alive and no one knows whether the same technique would work in ...